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Carbapenem-Resistant Enterobacteriaceae (CRE)

Enterobacteriaceae are a large family of different types of bacteria that commonly cause infections in healthcare settings. Examples include Escherichia coli (E. coli) and Klebsiella pneumoniae. Carbapenem-resistant Enterobacteriaceae (CRE) are a type of Enterobacteriaceae that are resistant to a group of antibiotics called carbapenems.

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Health Departments conducting these investigations are encouraged to consult with CDC by contacting the healthcare outbreak duty officer at

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CORHA Principles and Practices for Outbreak Response


The CORHA Principles and Practices for Outbreak Response: HAI/AR Pathogens (formerly known as High-Level Guidance) is intended as a comprehensive reference containing information specific to HAI/AR outbreak detection, reporting,...… Read More »

CORHA Proposed Investigation/Reporting Thresholds and Outbreak Definition for Carbapenem-Resistant Enterobacteriaceae (CRE)


The thresholds and outbreak definition presented below are based on available scientific resources and expert opinion and intended only as guidance; states and localities may have their own outbreak...… Read More »
Disclaimer: The positions and views expressed in these materials do not necessarily represent the official positions of CORHA’s member organizations.